News archive

Showing 1–10 of 28 results

New publications

Peptides used for transport of cargo over the cell membrane can have unwanted effects on calcium handling.

Per Kristian Lunde, Ornella Manfra, Thea Parsberg Støle, Marianne Lunde, Marita Martinsen, Cathrine Rein Carlson and William E. Louch

Polyarginine Cell-Penetrating Peptides Bind and Inhibit SERCA2

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Awards and prizes

Oslo University Hospital prize for outstanding research paper

Oslo University Hospital awards prizes every six months to six outstanding research articles featuring key authors from the hospital. On December 8th, the prizes were awarded for articles published in the first half of 2023. One of the winners was Harmonie Perdreau-Dahl, from the Louch Group at IEMR.

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People

People at IEMR: Jia Li

Jia Li is a postdoctoral fellow at IEMR, working with cardiomyocyte signaling and excitation contraction coupling. Her recent article shows how the contractile units of cardiac muscle cells function, and how they become dysfunctional during disease.

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New publications

How stretch brings harmony to the heart: a new article in Circulation Research

Li J, Sundnes J, Hou Y, Laasmaa M, Ruud M, Unger A, Kolstad TR, Frisk M, Norseng PA, Yang L, Setterberg IE, Alves ES, Kalakoutis M, Sejersted OM, Lanner JT, Linke WA, Lunde IG, de Tombe PP, Louch WE

Stretch Harmonizes Sarcomere Strain Across the Cardiomyocyte

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New publications

Understanding how 3 proteins work together to allow the maturation of heart muscle cells during development

Harmonie Perdreau-Dahl, David B. Lipsett, Michael Frisk, Fatemeh Kermani, Cathrine R. Carlson, Andreas Brech, Xin Shen, Anna Bergan-Dahl, Yufeng Hou, Tomi Tuomainen, Pasi Tavi, Peter P. Jones, Marianne Lunde, J. Andrew Wasserstrom, Jocelyn Laporte, Nina D. Ullrich, Geir Christensen, J. Preben Morth, William E. Louch

BIN1, myotubularin, and dynamin-2 coordinate t-tubule growth in cardiomyocytes

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New publications

Understanding how heart muscle cells are put together during development

Ornella Manfra, Samantha Louey, Sonnet S. Jonker, Harmonie Perdreau-Dahl, Michael Frisk, George D Giraud, Kent L. Thornburg, and William E. Louch

Augmenting Workload Drives T-tubule Assembly in Developing Cardiomyocytes

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New publications

A new article in Nature Cardiovascular Research shows how calcium release channels work together to trigger the heartbeat

Yufeng Hou, Martin Laasmaa, Jia Li, Xin Shen, Ornella Manfra, Einar S Nordén, Christopher Le, Lili Zhang, Ivar Sjaastad, Peter P Jones, Christian Soeller, William E Louch

Live-cell photoactivated localization microscopy correlates nanoscale ryanodine receptor configuration to calcium sparks in cardiomyocytes

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Seminars and conferences

IEMR – Project meeting,
Denis Reis de Assis

21. April 2023

“Estrogen rescues glucose metabolism but not calcium homeostasis in iPSC-derived neural progenitor cells from patients with schizophrenia”

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Seminars and conferences

IEMR – Project meeting,
Pete Jones

10. March 2023

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New publications

Tubulator: automated analysis of cardiomyocyte organelles and proteins in 3D

Frisk M, Norseng PA, Stenersen Espe EK, Louch WE

Tubulator: an automated approach to analysis of t-tubule and dyadic organization in cardiomyocytes

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