Funding
– Research Council of Norway
Academic interests
Exploring functional and structural differences of the cardiac dyad in health and disease by combining the usage of confocal and super-resolution microscopy (dSTORM, Electron Miscroscopy).
Research area
- Advanced light microscopy
- Arrhythmias
- Cardiomyocyte signaling
- Cardiomyopathies
- Excitation contraction coupling
- Heart failure
Latest publications
Frisk M, Le C, Shen X, Røe ÅT, Hou Y, Manfra O, Silva GJJ, van Hout I, Norden ES, Aronsen JM, Laasmaa M, Espe EKS, Zouein FA, Lambert RR, Dahl CP, Sjaastad I, Lunde IG, Coffey S, Cataliotti A, Gullestad L, Tønnessen T, Jones PP, Altara R, Louch WE (2021)
Etiology-Dependent Impairment of Diastolic Cardiomyocyte Calcium Homeostasis in Heart Failure With Preserved Ejection Fraction
J Am Coll Cardiol, 77 (4), 405-419
PubMed 33509397 DOI 10.1016/j.jacc.2020.11.044
Etiology-Dependent Impairment of Diastolic Cardiomyocyte Calcium Homeostasis in Heart Failure With Preserved Ejection Fraction
J Am Coll Cardiol, 77 (4), 405-419
PubMed 33509397 DOI 10.1016/j.jacc.2020.11.044
Ottesen AH, Carlson CR, Eken OS, Sadredini M, Myhre PL, Shen X, Dalhus B, Laver DR, Lunde PK, Kurola J, Lunde M, Hoff JE, Godang K, Sjaastad I, Pettilä V, Stridsberg M, Lehnart SE, Edwards AG, Lunde IG, Omland T, Stokke MK, Christensen G, Røsjø H, Louch WE (2019)
Secretoneurin Is an Endogenous Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor That Attenuates Ca2+-Dependent Arrhythmia
Circ Arrhythm Electrophysiol, 12 (4), e007045
PubMed 30943765 DOI 10.1161/CIRCEP.118.007045
Secretoneurin Is an Endogenous Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor That Attenuates Ca2+-Dependent Arrhythmia
Circ Arrhythm Electrophysiol, 12 (4), e007045
PubMed 30943765 DOI 10.1161/CIRCEP.118.007045
Shen X, van den Brink J, Hou Y, Colli D, Le C, Kolstad TR, MacQuaide N, Carlson CR, Kekenes-Huskey PM, Edwards AG, Soeller C, Louch WE (2018)
3D dSTORM imaging reveals novel detail of ryanodine receptor localization in rat cardiac myocytes
J Physiol, 597 (2), 399-418
PubMed 30412283 DOI 10.1113/JP277360
3D dSTORM imaging reveals novel detail of ryanodine receptor localization in rat cardiac myocytes
J Physiol, 597 (2), 399-418
PubMed 30412283 DOI 10.1113/JP277360
Munro ML, Shen X, Ward M, Ruygrok PN, Crossman DJ, Soeller C (2018)
Highly variable contractile performance correlates with myocyte content in trabeculae from failing human hearts
Sci Rep, 8 (1), 2957
PubMed 29440728 DOI 10.1038/s41598-018-21199-y
Highly variable contractile performance correlates with myocyte content in trabeculae from failing human hearts
Sci Rep, 8 (1), 2957
PubMed 29440728 DOI 10.1038/s41598-018-21199-y