News archive

A novel understanding of the matrix protein lumican in hypertrophic cardiomyopathy (HCM)

Rixon C, Andreassen K, Shen X, Erusappan PM, Almaas VM, Palmero S, Dahl CP, Ueland T, Sjaastad I, Louch WE, Stokke MK, Tønnessen T, Christensen G, Lunde IG

Lumican accumulates with fibrillar collagen in fibrosis in hypertrophic cardiomyopathy

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The extracellular matrix protein ‘ADAMTSL3’ is crucial for preserving cardiac structure and function in heart failure

Karoline B Rypdal, A Olav Melleby, Emma L Robinson, Jia Li, Sheryl Palmero, Deborah E Seifert, Daniel Martin, Catelyn Clark, Begoña López, Kristine Andreassen, Christen P Dahl, Ivar Sjaastad, Theis Tønnessen, Mathis K Stokke, William E Louch, Arantxa González, Stephane Heymans, Geir Christensen, Suneel S Apte, Ida G Lunde

ADAMTSL3 knock-out mice develop cardiac dysfunction and dilatation with increased TGFβ signalling after pressure overload

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New insights into reperfusion arrhythmias

CaMKII and reactive oxygen species contribute to early reperfusion arrhythmias, but oxidation of CaMKIIδ at methionines 281/282 is not a determining factor.

Calcineurin-NFAT dynamics corresponds to cardiac remodeling during aortic banding and debanding, mimicking aortic valve replacement

Ida G. Lunde, Biljana Skrbic, Ivar Sjaastad, Geir Christensen, Cathrine R. Carlson, Theis Tønnessen

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MicroRNAs Diagnostic Performance in Heart Failure: a Systematic Review and Meta-Analysis

Reza Parvan, Milad Hosseinpour, Yousef Moradi, Yvan Devaux, Alessandro Cataliotti, Gustavo J.J. da Silva

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Cardiomyocyte-specific overexpression of syndecan-4 in mice results in activation of calcineurin-NFAT signalling and exacerbated cardiac hypertrophy

Lunde IG, Aronsen JM, Melleby AO, Strand ME, Skogestad J, Bendiksen BA, Ahmed MS, Sjaastad I, Attramadal H, Carlson CR, Christensen G.

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