Image: Profile picture of William (Bill) E. Louch

William (Bill) Louch

Group Leader & Professor

Louch group

Email: w.e.louch@medisin.uio.no
Phone: +47 230 16793

Education
2001 PhD Pharmacology, Dalhousie University, Halifax, Canada
1997 BSc Chemistry/Neuroscience, Dalhousie University, Halifax, Canada

Positions
2018- Secretary General, The Scandinavian Physiological Society
2015- Professor of Medicine, IEMR
2015- Treasurer, Federation of European Physiological Sciences (FEPS),
2013- Head, Core Facility for Advanced Light Microscopy, OUH

Funding
– European Research Council Consolidator Grant
– Research Council of Norway Researcher Grant, Mobility Grant
– National Association for Public Health (2 postdoctoral grants)
– South-Eastern Norway Regional Health Authority (PhD student, postdoc grants)

Awards, committees and memberships
2020- Head of Organizing Committee –“Europhysiology” meeting in Copenhagen, 2022.
2018- Organizer, Cardiac Physiology Satellite Meeting, Europhysiology, London, UK.
2017- Partner, KG Jebsen Center for Cardiac Research
2015 Digitalis Pupurea Award for Research Excellence, University of Oslo Medical Faculty

Research area

  • Advanced light microscopy
  • Arrhythmias
  • Diastolic dysfunction
  • Electrophysiology
  • Excitation contraction coupling
  • Heart failure
  • Imaging

Latest publications

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Hernández Mesa M, van den Brink J, Louch WE, McCabe KJ, Rangamani P (2022)
Nanoscale organization of ryanodine receptor distribution and phosphorylation pattern determines the dynamics of calcium sparks
PLoS Comput Biol, 18 (6), e1010126
PubMed 35666763 DOI 10.1371/journal.pcbi.1010126
De Genst E, Foo KS, Xiao Y, Rohner E, de Vries E, Sohlmér J, Witman N, Hidalgo A, Kolstad TRS, Louch WE, Pehrsson S, Park A, Ikeda Y, Li X, Mayr LM, Wickson K, Jennbacken K, Hansson K, Fritsche-Danielson R, Hunt J, Chien KR (2022)
Blocking phospholamban with VHH intrabodies enhances contractility and relaxation in heart failure
Nat Commun, 13 (1), 3018
PubMed 35641497 DOI 10.1038/s41467-022-29703-9
Louch WE (2022)
A TRP to the emergency room: Understanding arrhythmia in the ageing heart
Cardiovasc Res, 118 (4), 932-933
PubMed 35225325 DOI 10.1093/cvr/cvac017
Louch WE, Perdreau-Dahl H, Edwards AG (2022)
Image-Driven Modeling of Nanoscopic Cardiac Function: Where Have We Come From, and Where Are We Going?
Front Physiol, 13, 834211
PubMed 35356084 DOI 10.3389/fphys.2022.834211
Sommese LM, Racioppi MF, Shen X, Orlowski A, Valverde CA, Louch WE, Vila Petroff M, Gonano LA (2022)
Discordant Ca2+ release in cardiac myocytes: characterization and susceptibility to pharmacological RyR2 modulation
Pflugers Arch, 474 (6), 625-636
PubMed 35235009 DOI 10.1007/s00424-022-02678-8
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