William (Bill) Louch

Group Leader & Professor

Louch group

Email: w.e.louch@medisin.uio.no
Phone: +47 230 16793

Education
2001 PhD Pharmacology, Dalhousie University, Halifax, Canada
1997 BSc Chemistry/Neuroscience, Dalhousie University, Halifax, Canada

Positions
2018- Secretary General, The Scandinavian Physiological Society
2015- Professor of Medicine, IEMR
2015- Treasurer, Federation of European Physiological Sciences (FEPS),
2013- Head, Core Facility for Advanced Light Microscopy, OUH

Funding
– European Research Council Consolidator Grant
– Research Council of Norway Researcher Grant, Mobility Grant
– National Association for Public Health (2 postdoctoral grants)
– South-Eastern Norway Regional Health Authority (PhD student, postdoc grants)

Awards, committees and memberships
2020- Head of Organizing Committee –“Europhysiology” meeting in Copenhagen, 2022.
2018- Organizer, Cardiac Physiology Satellite Meeting, Europhysiology, London, UK.
2017- Partner, KG Jebsen Center for Cardiac Research
2015 Digitalis Pupurea Award for Research Excellence, University of Oslo Medical Faculty

Research area

Advanced light microscopy
Arrhythmias
Diastolic dysfunction
Electrophysiology
Excitation contraction coupling
Heart failure
Imaging

Latest publications

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Zhang X, Wu Y, Smith C, Louch WE, Morotti S, Dobrev D, Grandi E, Ni H (2024)
Enhanced Ca2+-Driven Arrhythmias in Female Patients with Atrial Fibrillation: Insights from Computational Modeling
bioRxiv
PubMed 38496584 DOI 10.1101/2024.03.04.583217

Lunde PK, Manfra O, Støle TP, Lunde M, Martinsen M, Carlson CR, Louch WE (2023)
Polyarginine Cell-Penetrating Peptides Bind and Inhibit SERCA2
Cells, 12 (19)
PubMed 37830576 DOI 10.3390/cells12192358

Laasmaa M, Branovets J, Stolova J, Shen X, Rätsepso T, Balodis MJ, Grahv C, Hendrikson E, Louch WE, Birkedal R, Vendelin M (2023)
Cardiomyocytes from female compared to male mice have larger ryanodine receptor clusters and higher calcium spark frequency
J Physiol, 601 (18), 4033-4052
PubMed 37561554 DOI 10.1113/JP284515

Li J, Sundnes J, Hou Y, Laasmaa M, Ruud M, Unger A, Kolstad TR, Frisk M, Norseng PA, Yang L, Setterberg IE, Alves ES, Kalakoutis M, Sejersted OM, Lanner JT, Linke WA, Lunde IG, de Tombe PP, Louch WE (2023)
Stretch Harmonizes Sarcomere Strain Across the Cardiomyocyte
Circ Res, 133 (3), 255-270
PubMed 37401464 DOI 10.1161/CIRCRESAHA.123.322588

Perdreau-Dahl H, Lipsett DB, Frisk M, Kermani F, Carlson CR, Brech A, Shen X, Bergan-Dahl A, Hou Y, Tuomainen T, Tavi P, Jones PP, Lunde M, Wasserstrom JA, Laporte J, Ullrich ND, Christensen G, Morth JP, Louch WE (2023)
BIN1, Myotubularin, and Dynamin-2 Coordinate T-Tubule Growth in Cardiomyocytes
Circ Res, 132 (11), e188-e205
PubMed 37139790 DOI 10.1161/CIRCRESAHA.122.321732

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