Image: Profile picture of William (Bill) E. Louch

William (Bill) Louch

Group Leader & Professor

Louch group

Education
2001 PhD Pharmacology, Dalhousie University, Halifax, Canada
1997 BSc Chemistry/Neuroscience, Dalhousie University, Halifax, Canada

Positions
2018- Secretary General, The Scandinavian Physiological Society
2015- Professor of Medicine, IEMR
2015- Treasurer, Federation of European Physiological Sciences (FEPS),
2013- Head, Core Facility for Advanced Light Microscopy, OUH

Funding
– European Research Council Consolidator Grant
– Research Council of Norway Researcher Grant, Mobility Grant
– National Association for Public Health (2 postdoctoral grants)
– South-Eastern Norway Regional Health Authority (PhD student, postdoc grants)

Awards, committees and memberships
2020- Head of Organizing Committee –“Europhysiology” meeting in Copenhagen, 2022.
2018- Organizer, Cardiac Physiology Satellite Meeting, Europhysiology, London, UK.
2017- Partner, KG Jebsen Center for Cardiac Research
2015 Digitalis Pupurea Award for Research Excellence, University of Oslo Medical Faculty

Research area

  • Advanced light microscopy
  • Arrhythmias
  • Diastolic dysfunction
  • Electrophysiology
  • Excitation contraction coupling
  • Heart failure
  • Imaging

Latest publications

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Rohner E, Witman N, Sohlmer J, De Genst E, Louch WE, Sahara M, Chien KR (2021)
An mRNA assay system demonstrates proteasomal-specific degradation contributes to cardiomyopathic phospholamban null mutation
Mol Med, 27 (1), 102
PubMed 34496741 DOI 10.1186/s10020-021-00362-8
Grote Beverborg N, Später D, Knöll R, Hidalgo A, Yeh ST, Elbeck Z, Silljé HHW, Eijgenraam TR, Siga H, Zurek M, Palmér M, Pehrsson S, Albery T, Bomer N, Hoes MF, Boogerd CJ, Frisk M, van Rooij E, Damle S, Louch WE, Wang QD, Fritsche-Danielson R, Chien KR, Hansson KM, Mullick AE, de Boer RA, van der Meer P (2021)
Phospholamban antisense oligonucleotides improve cardiac function in murine cardiomyopathy
Nat Commun, 12 (1), 5180
PubMed 34462437 DOI 10.1038/s41467-021-25439-0
Sadredini M, Haugsten Hansen M, Frisk M, Louch WE, Lehnart SE, Sjaastad I, Stokke MK (2021)
CaMKII inhibition has dual effects on spontaneous Ca2+ release and Ca2+ alternans in ventricular cardiomyocytes from mice with a gain-of-function RyR2 mutation
Am J Physiol Heart Circ Physiol, 321 (2), H446-H460
PubMed 34270372 DOI 10.1152/ajpheart.00011.2021
Frisk M, Le C, Shen X, Røe ÅT, Hou Y, Manfra O, Silva GJJ, van Hout I, Norden ES, Aronsen JM, Laasmaa M, Espe EKS, Zouein FA, Lambert RR, Dahl CP, Sjaastad I, Lunde IG, Coffey S, Cataliotti A, Gullestad L, Tønnessen T, Jones PP, Altara R, Louch WE (2021)
Etiology-Dependent Impairment of Diastolic Cardiomyocyte Calcium Homeostasis in Heart Failure With Preserved Ejection Fraction
J Am Coll Cardiol, 77 (4), 405-419
PubMed 33509397 DOI 10.1016/j.jacc.2020.11.044
Danielsen TK, Sadredini M, Manotheepan R, Aronsen JM, Frisk M, Hansen MH, Andressen KW, Hougen K, Levy FO, Louch WE, Sejersted OM, Sjaastad I, Stokke MK (2021)
Exercise Training Stabilizes RyR2-Dependent Ca2+ Release in Post-infarction Heart Failure
Front Cardiovasc Med, 7, 623922
PubMed 33569394 DOI 10.3389/fcvm.2020.623922
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