Image: Profile picture of William (Bill) E. Louch

William (Bill) Louch

Group Leader & Professor

Louch group

Email: w.e.louch@medisin.uio.no
Phone: +47 230 16793

Education
2001 PhD Pharmacology, Dalhousie University, Halifax, Canada
1997 BSc Chemistry/Neuroscience, Dalhousie University, Halifax, Canada

Positions
2018- Secretary General, The Scandinavian Physiological Society
2015- Professor of Medicine, IEMR
2015- Treasurer, Federation of European Physiological Sciences (FEPS),
2013- Head, Core Facility for Advanced Light Microscopy, OUH

Funding
– European Research Council Consolidator Grant
– Research Council of Norway Researcher Grant, Mobility Grant
– National Association for Public Health (2 postdoctoral grants)
– South-Eastern Norway Regional Health Authority (PhD student, postdoc grants)

Awards, committees and memberships
2020- Head of Organizing Committee –“Europhysiology” meeting in Copenhagen, 2022.
2018- Organizer, Cardiac Physiology Satellite Meeting, Europhysiology, London, UK.
2017- Partner, KG Jebsen Center for Cardiac Research
2015 Digitalis Pupurea Award for Research Excellence, University of Oslo Medical Faculty

Research area

  • Advanced light microscopy
  • Arrhythmias
  • Diastolic dysfunction
  • Electrophysiology
  • Excitation contraction coupling
  • Heart failure
  • Imaging

Latest publications

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Frisk M, Norseng PA, Stenersen Espe EK, Louch WE (2022)
Tubulator: an automated approach to analysis of t-tubule and dyadic organization in cardiomyocytes
Philos Trans R Soc Lond B Biol Sci, 377 (1864), 20210468
PubMed 36189810 DOI 10.1098/rstb.2021.0468
Zhang X, Smith CER, Morotti S, Edwards AG, Sato D, Louch WE, Ni H, Grandi E (2022)
Mechanisms of spontaneous Ca2+ release-mediated arrhythmia in a novel 3D human atrial myocyte model: II Ca2+ -handling protein variation
J Physiol
PubMed 36114707 DOI 10.1113/JP283602
Zhang X, Ni H, Morotti S, Smith CER, Sato D, Louch WE, Edwards AG, Grandi E (2022)
Mechanisms of spontaneous Ca2+ release-mediated arrhythmia in a novel 3D human atrial myocyte model: I. Transverse-axial tubule variation
J Physiol
PubMed 36094888 DOI 10.1113/JP283363
Støle TP, Lunde M, Shen X, Martinsen M, Lunde PK, Li J, Lockwood F, Sjaastad I, Louch WE, Aronsen JM, Christensen G, Carlson CR (2022)
The female syndecan-4-/- heart has smaller cardiomyocytes, augmented insulin/pSer473-Akt/pSer9-GSK-3β signaling, and lowered SCOP, pThr308-Akt/Akt and GLUT4 levels
Front Cell Dev Biol, 10, 908126
PubMed 36092718 DOI 10.3389/fcell.2022.908126
Shen X, van den Brink J, Bergan-Dahl A, Kolstad TR, Norden ES, Hou Y, Laasmaa M, Aguilar-Sanchez Y, Quick AP, Espe EKS, Sjaastad I, Wehrens XHT, Edwards AG, Soeller C, Louch WE (2022)
Prolonged β-adrenergic stimulation disperses ryanodine receptor clusters in cardiomyocytes and has implications for heart failure
Elife, 11
PubMed 35913125 DOI 10.7554/eLife.77725
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