News archive | Institute for Experimental Medical Research (IEMR)

New publications

Brugada syndrome and biological complexity – reflections on the importance of translational research

Mathis Korseberg Stokke, Markéta Bébarová

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Lessons on the non-linear path of medical progress and biological complexity from mouse models of the Brugada syndrome

New publications

Cardiomyocytes respond to changes in workload by altering their substructure and function

Ruud M, Frisk M, Melleby AO, Norseng PA, Mohamed BA, Li J, Aronsen JM, Setterberg IE, Jakubiczka J, van Hout I, Coffey S, Shen X, Nygård S, Lunde IG, Tønnessen T, Jones PP, Sjaastad I, Gullestad L, Toischer K, Dahl CP, Christensen G, Louch WE

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Regulation of cardiomyocyte t-tubule structure by preload and afterload: Roles in cardiac compensation and decompensation

New publications

Peptides used for transport of cargo over the cell membrane can have unwanted effects on calcium handling.

Per Kristian Lunde, Ornella Manfra, Thea Parsberg Støle, Marianne Lunde, Marita Martinsen, Cathrine Rein Carlson and William E. Louch

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Polyarginine Cell-Penetrating Peptides Bind and Inhibit SERCA2

New publications

New editorial on the “forgotten” heart chamber

Emil Espe, Mathis Korseberg Stokke

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Editorial for “MRI Assessment of Myocardial Deformation for Risk Stratification of Major Arrhythmic Events in Patients with Non-Ischemic Cardiomyopathy Eligible for Primary Prevention Implantable Cardioverter Defibrillators”

New publications

Understanding the stiff heart: Versican in cardiac fibrosis development

Athiramol Sasi, Andreas Romaine, Pugazendhi Murugan Erusappan, Arne Olav Melleby, Almira Hasic, Christen Peder Dahl, Kaspar Broch, Vibeke Marie Almaas, Rosa Doñate Puertas, H Llewelyn Roderick, Ida Gjervold Lunde, Ivar Sjaastad, Maria Vistnes, Geir Christensen

Temporal expression and spatial distribution of the proteoglycan versican during cardiac fibrosis development

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New publications

How stretch brings harmony to the heart: a new article in Circulation Research

Li J, Sundnes J, Hou Y, Laasmaa M, Ruud M, Unger A, Kolstad TR, Frisk M, Norseng PA, Yang L, Setterberg IE, Alves ES, Kalakoutis M, Sejersted OM, Lanner JT, Linke WA, Lunde IG, de Tombe PP, Louch WE

Stretch Harmonizes Sarcomere Strain Across the Cardiomyocyte

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New publications

Neutral effect of antioxidant therapy for reperfusion arrhythmias shows value of pigs in preclinical research

Marie Haugsten Hansen, Mani Sadredini, Almira Hasic, Morten Eriksen and Mathis Korseberg Stokke

Myocardial oxidative stress is increased in early reperfusion, but systemic antioxidative therapy does not prevent ischemia-reperfusion arrhythmias in pigs

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New publications

Challenging the utility of common ECG patterns

Stine Aagaard-Nilsen, Lars Andreas Dejgaard, Ole-Gunnar Anfinsen, Erik Lyseggen, Torbjørn Holm, Trine Synnøve Fink, Hans Henrik Odland, Knut Sevre, Erik Kongsgård, Finn Hegbom, Mathis Korseberg Stokke

Utility of the Inferior Axis and Left Bundle Branch Block Pattern for Categorization of Patients With Premature Ventricular Complexes Before Catheter Ablation

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New publications

FTIR analysis eases the assessment of organ damage and tailored treatment of heart failure

Leonardo Pioppi, Niki Tombolesi, Reza Parvan, Gustavo Jose Justo da Silva, Raffaele Altara, Marco Paolantoni, Assunta Morresi, Paola Sassi and Alessandro Cataliotti

FTIR Analysis of Renal Tissue for Assessment of Hypertensive Organ Damage and proANP31-67 Treatment

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New publications

Understanding how 3 proteins work together to allow the maturation of heart muscle cells during development

Harmonie Perdreau-Dahl, David B. Lipsett, Michael Frisk, Fatemeh Kermani, Cathrine R. Carlson, Andreas Brech, Xin Shen, Anna Bergan-Dahl, Yufeng Hou, Tomi Tuomainen, Pasi Tavi, Peter P. Jones, Marianne Lunde, J. Andrew Wasserstrom, Jocelyn Laporte, Nina D. Ullrich, Geir Christensen, J. Preben Morth, William E. Louch

BIN1, myotubularin, and dynamin-2 coordinate t-tubule growth in cardiomyocytes

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