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Showing 1–10 of 31 results

New publications

A novel understanding of the matrix protein lumican in hypertrophic cardiomyopathy (HCM)

Rixon C, Andreassen K, Shen X, Erusappan PM, Almaas VM, Palmero S, Dahl CP, Ueland T, Sjaastad I, Louch WE, Stokke MK, Tønnessen T, Christensen G, Lunde IG

Lumican accumulates with fibrillar collagen in fibrosis in hypertrophic cardiomyopathy

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New publications

The extracellular matrix protein ‘ADAMTSL3’ is crucial for preserving cardiac structure and function in heart failure

Karoline B RypdalA Olav MellebyEmma L RobinsonJia LiSheryl PalmeroDeborah E SeifertDaniel MartinCatelyn ClarkBegoña LópezKristine AndreassenChristen P DahlIvar SjaastadTheis TønnessenMathis K StokkeWilliam E LouchArantxa GonzálezStephane HeymansGeir ChristensenSuneel S ApteIda G Lunde

ADAMTSL3 knock-out mice develop cardiac dysfunction and dilatation with increased TGFβ signalling after pressure overload

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New publications

New insights into reperfusion arrhythmias

CaMKII and reactive oxygen species contribute to early reperfusion arrhythmias, but oxidation of CaMKIIδ at methionines 281/282 is not a determining factor.

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New publications

Calcineurin-NFAT dynamics corresponds to cardiac remodeling during aortic banding and debanding, mimicking aortic valve replacement

Ida G. Lunde, Biljana Skrbic, Ivar Sjaastad, Geir Christensen, Cathrine R. Carlson, Theis Tønnessen

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New publications

MicroRNAs Diagnostic Performance in Heart Failure: a Systematic Review and Meta-Analysis

Reza Parvan, Milad Hosseinpour, Yousef Moradi, Yvan Devaux, Alessandro Cataliotti, Gustavo J.J. da Silva

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New publications

Cardiomyocyte-specific overexpression of syndecan-4 in mice results in activation of calcineurin-NFAT signalling and exacerbated cardiac hypertrophy

Lunde IG, Aronsen JM, Melleby AO, Strand ME, Skogestad J, Bendiksen BAAhmed MS, Sjaastad I, Attramadal H, Carlson CR, Christensen G.

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New publications

Tubulator: automated analysis of cardiomyocyte organelles and proteins in 3D

Frisk M, Norseng PA, Stenersen Espe EK, Louch WE

Tubulator: an automated approach to analysis of t-tubule and dyadic organization in cardiomyocytes

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New publications

A rhythmic collaboration: Key articles from IEMR for Norwegian Cardiologists caring for patients with PVCs

Premature ventricular complexes (PVC) is one of the most common ventricular arrhythmias encountered in clinical practice, and although most often benign, may cause debilitating symptoms, risk of left ventricular dysfunction, or life-threatening arrhythmias.

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New publications

Using MR elastography to measure the hearts stiffness

Smith L, Skulberg V, Zhang L, Sjaastad I, Espe E (2022)

The effects of geometry on stiffness measurements in high-field magnetic resonance elastography: A study on rodent cardiac phantoms

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New publications

Signaling protein Syndecan-4 reveals new knowledge of the female heart

Støle TP, Lunde M, Shen X, Martinsen M, Lunde PK, Li J, Lockwood F, Sjaastad I, Louch WE, Aronsen JM, Christensen G, Carlson CR (2022)

The female syndecan-4-/- heart has smaller cardiomyocytes, augmented insulin/pSer473-Akt/pSer9-GSK-3β signaling, and lowered SCOP, pThr308-Akt/Akt and GLUT4 levels

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