Image: Profile picture of Alessandro Cataliotti

Alessandro Cataliotti

Group Leader & Professor

Cataliotti group

Phone: +47 2301 6807

MD, PhD, Specialist in Internal Medicine

UiO and OUH employee

Awards, committees and memberships
Recipient, as principal investigator, of several national and international awards and scientific recognitions including NIH R01 grants, a Doris Duke Charitable Foundation Scientific Development grant, Helse Sør Øst grants, Nasjonaforeiningen for Folkehelsen grants, the American Society of Hypertension Young Scholar Award, and several others from both public institutions and private foundations.

Academic interests
My general research interests include cardiac endocrinology and physiology in human and experimental models of cardiovascular and renal diseases, such as congestive heart failure, hypertension, atherosclerosis, and renal failure. I have a particular interest in the natriuretic peptides and their regulatory actions on cardiovascular and renal homeostasis in hypertension, heart failure and renal dysfunction. This interest has led to the development of natriuretic peptide based chronic therapy (oral, subcutaneous, and gene delivery). I have been the principal investigator (PI) of an NIH funded grant on innovative gene delivery strategies for the treatment of organ damage secondary to hypertension, e.g. hypertensive heart disease and renal fibrosis and dysfunction. I led studies focusing on the effects of natriuretic peptides treatment in preclinical models of diastolic dysfunction and humans with hypertension resistant to standard treatment. My interest is also on cardiorenal epidemiology and biomarkers development and discovery of novel drugs for the treatment of cardiovascular and renal diseases. My research resulted in the publications of more that hundred manuscripts and in five patents.

Research area

  • Cardiorenal syndrome
  • Diastolic dysfunction
  • Heart failure
  • Hypertension
  • Ischemic heart disease

Latest publications

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Pioppi L, Parvan R, Samrend A, Silva GJJ, Paolantoni M, Sassi P, Cataliotti A (2023)
Vibrational spectroscopy identifies myocardial chemical modifications in heart failure with preserved ejection fraction
J Transl Med, 21 (1), 617
PubMed 37697391 DOI 10.1186/s12967-023-04465-0
Andresen H, Pérez-Ternero C, Robinson J, Dickey DM, Hobbs AJ, Potter LR, Levy FO, Cataliotti A, Moltzau LR (2023)
Novel enhancers of guanylyl cyclase-A activity acting via allosteric modulation
Br J Pharmacol, 180 (24), 3254-3270
PubMed 37522273 DOI 10.1111/bph.16203
Pioppi L, Tombolesi N, Parvan R, da Silva GJJ, Altara R, Paolantoni M, Morresi A, Sassi P, Cataliotti A (2023)
FTIR Analysis of Renal Tissue for the Assessment of Hypertensive Organ Damage and proANP31-67 Treatment
Int J Mol Sci, 24 (6)
PubMed 36982271 DOI 10.3390/ijms24065196
Parvan R, Hosseinpour M, Moradi Y, Devaux Y, Cataliotti A, da Silva GJJ (2022)
Diagnostic performance of microRNAs in the detection of heart failure with reduced or preserved ejection fraction: a systematic review and meta-analysis
Eur J Heart Fail, 24 (12), 2212-2225
PubMed 36161443 DOI 10.1002/ejhf.2700
Tombolesi N, Altara R, da Silva GJJ, Tannous C, Zouein FA, Stensløkken KO, Morresi A, Paolantoni M, Booz GW, Cataliotti A, Sassi P (2022)
Early cardiac-chamber-specific fingerprints in heart failure with preserved ejection fraction detected by FTIR and Raman spectroscopic techniques
Sci Rep, 12 (1), 3440
PubMed 35236899 DOI 10.1038/s41598-022-07390-2
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