Cataliotti group: The endocrine function of the heart

Cataliotti group

The main focus of our group is to study the role of hormones produced by the heart during the early stages of human cardiovascular and renal dysfunction.

Starting from the understanding of the existence of an impaired endocrine function of the heart that underlies several cardiovascular and renal diseases in humans, our group investigates the hormonal function of the heart in both physiological and pathophysiological conditions.

The main focus of our group is to study the role of hormones produced by the heart during the early stages of human cardiovascular and renal dysfunction, such as hypertension, stage A-B heart failure, ischemic cardiomyopathy, and mild to moderate renal impairment. Our group has a highly translational approach, performing both clinical studies, and preclinical research using innovative delivery approaches, as well as new therapeutic agents such as alternative forms of natriuretic peptides.

Alessandro Cataliotti is a Professor of Medicine and has joined the University of Oslo at the IEMR three years ago after conducting extensive research in the field of cardiovascular disease in the USA at the prestigious location of the Mayo Clinic Foundation. He has conducted several preclinical and clinical studies to evaluate the effects of cardiac hormones in the setting of cardiovascular and renal dysfunction and has received numerous international scientific awards and nominations in recognition of his work.

Our group is also committed to the discovery of novel small molecules that can enhance the activity of the cardiac peptides, and to further elucidate the mechanisms of actions of molecules known to interfere with the activity of several cardiac hormones.

Group Leader

Alessandro Cataliotti

Group Leader & Professor

Group members

Einar Sjaastad Nordén

Doctoral Research Fellow

Gustavo Justo da Silva

Postdoctoral fellow

Henriette Andresen

Doctoral Research Fellow

Kaja Knudsen Bergo

Doctoral Research Fellow

Raffaele Altara

Postdoctoral fellow

Reza Parvan

Doctoral Research Fellow

Latest publications

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Tombolesi N, Altara R, da Silva GJJ, Tannous C, Zouein FA, Stensløkken KO, Morresi A, Paolantoni M, Booz GW, Cataliotti A, Sassi P (2022)
Early cardiac-chamber-specific fingerprints in heart failure with preserved ejection fraction detected by FTIR and Raman spectroscopic techniques
Sci Rep, 12 (1), 3440
PubMed 35236899 DOI 10.1038/s41598-022-07390-2
Habeichi NJ, Tannous C, Yabluchanskiy A, Altara R, Mericskay M, Booz GW, Zouein FA (2021)
Insights into the modulation of the interferon response and NAD+ in the context of COVID-19
Int Rev Immunol
PubMed 34378474 DOI 10.1080/08830185.2021.1961768
da Silva GJJ, Altara R, Booz GW, Cataliotti A (2021)
Atrial Natriuretic Peptide31-67: A Novel Therapeutic Factor for Cardiovascular Diseases
Front Physiol, 12, 691407
PubMed 34305645 DOI 10.3389/fphys.2021.691407
Kaplan A, Altara R, Manca M, Gunes HM, Cataliotti A, Booz GW, Zouein FA (2021)
Distorted assessment of left atrial size by echocardiography in patients with increased aortic root diameter
Egypt Heart J, 73 (1), 55
PubMed 34173898 DOI 10.1186/s43044-021-00177-2
Zouein FA, Altara R, Massoud GP, Booz GW (2021)
The Angiotensin II Type 1(AT1) Receptor and Cardiac Hypertrophy: Did We Have It Wrong All Along?
J Cardiovasc Pharmacol, 77 (5), 531-535
PubMed 33657051 DOI 10.1097/FJC.0000000000000999
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