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More evidence for exercise at young age in hypertrophic cardiomyopathy

Exercise training during childhood and adolescence is associated with favorable diastolic function in hypertrophic cardiomyopathy.

Kristine Andreassen, Lars A. Dejgaard, Øyvind Lie, Trine S. Fink, Ida G. Lunde, Thor Edvardsen, Kristina H. Haugaa, Mathis K. Stokke.

Historically, patients with hypertrophic cardiomyopathy were advised against exercise and sports participation, due to a perceived risk of arrhythmias and sudden cardiac death. However, recent work have indicated that sudden cardiac death occurs primarily during rest or light activity. In the present paper from IEMR, PhD student Kristine Andreassen and colleagues show that exercise performed during young age is associated with better diastolic function in these patients. The study was based on a questionnaire on exercise history and echocardiographic examination of 187 patients. The data are in line with personalized advice on exercise in patients with hypertrophic cardiomyopathy recommended in recent guidelines.

The project is the result of a collaboration between the Stokke group at IEMR, and Profs. Kristina Haugaa and Thor Edvardsen at Dept. of Cardiology Rikshospitalet.

PMID: 35714718

DOI: 10.1016/j.ijcard.2022.06.042

Kristine Andreassen

Doctoral Research Fellow

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Mathis Korseberg Stokke

Head of Department & Group Leader & Professor & Senior Consultant

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Institute for Experimental Medical Research

Oslo University Hospital, Ullevål

PB 4956 Nydalen

NO-0424 Oslo

Norway

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