Strand ME, Vanhaverbeke M, Henkens MTHM, Sikking MA, Rypdal KB, Braathen B, Almaas VM, Tønnessen T, Christensen G, Heymans S, Lunde IG (2023)
Inflammation and Syndecan-4 Shedding from Cardiac Cells in Ischemic and Non-Ischemic Heart Disease
Biomedicines, 11 (4)
PubMed
37189684 DOI
10.3390/biomedicines11041066Lunde IG, Aronsen JM, Melleby AO, Strand ME, Skogestad J, Bendiksen BA, Ahmed MS, Sjaastad I, Attramadal H, Carlson CR, Christensen G (2022)
Cardiomyocyte-specific overexpression of syndecan-4 in mice results in activation of calcineurin-NFAT signalling and exacerbated cardiac hypertrophy
Mol Biol Rep, 49 (12), 11795-11809
PubMed
36205855 DOI
10.1007/s11033-022-07985-yRypdal KB, Erusappan PM, Melleby AO, Seifert DE, Palmero S, Strand ME, Tønnessen T, Dahl CP, Almaas V, Hubmacher D, Apte SS, Christensen G, Lunde IG (2021)
The extracellular matrix glycoprotein ADAMTSL2 is increased in heart failure and inhibits TGFβ signalling in cardiac fibroblasts
Sci Rep, 11 (1), 19757
PubMed
34611183 DOI
10.1038/s41598-021-99032-2Herum KM, Romaine A, Wang A, Melleby AO, Strand ME, Pacheco J, Braathen B, Dunér P, Tønnessen T, Lunde IG, Sjaastad I, Brakebusch C, McCulloch AD, Gomez MF, Carlson CR, Christensen G (2020)
Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin
J Am Heart Assoc, 9 (3), e013518
PubMed
32000579 DOI
10.1161/JAHA.119.013518Mohammadzadeh N, Lunde IG, Andenæs K, Strand ME, Aronsen JM, Skrbic B, Marstein HS, Bandlien C, Nygård S, Gorham J, Sjaastad I, Chakravarti S, Christensen G, Engebretsen KVT, Tønnessen T (2019)
The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload
Sci Rep, 9 (1), 9206
PubMed
31235849 DOI
10.1038/s41598-019-45651-9Andenæs K, Lunde IG, Mohammadzadeh N, Dahl CP, Aronsen JM, Strand ME, Palmero S, Sjaastad I, Christensen G, Engebretsen KVT, Tønnessen T (2018)
The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling
PLoS One, 13 (7), e0201422
PubMed
30052659 DOI
10.1371/journal.pone.0201422Melleby AO, Strand ME, Romaine A, Herum KM, Skrbic B, Dahl CP, Sjaastad I, Fiane AE, Filmus J, Christensen G, Lunde IG (2016)
The Heparan Sulfate Proteoglycan Glypican-6 Is Upregulated in the Failing Heart, and Regulates Cardiomyocyte Growth through ERK1/2 Signaling
PLoS One, 11 (10), e0165079
PubMed
27768722 DOI
10.1371/journal.pone.0165079Strand ME, Aronsen JM, Braathen B, Sjaastad I, Kvaløy H, Tønnessen T, Christensen G, Lunde IG (2015)
Shedding of syndecan-4 promotes immune cell recruitment and mitigates cardiac dysfunction after lipopolysaccharide challenge in mice
J Mol Cell Cardiol, 88, 133-44
PubMed
26449522 DOI
10.1016/j.yjmcc.2015.10.003Skrbic B, Engebretsen KV, Strand ME, Lunde IG, Herum KM, Marstein HS, Sjaastad I, Lunde PK, Carlson CR, Christensen G, Bjørnstad JL, Tønnessen T (2015)
Lack of collagen VIII reduces fibrosis and promotes early mortality and cardiac dilatation in pressure overload in mice
Cardiovasc Res, 106 (1), 32-42
PubMed
25694587 DOI
10.1093/cvr/cvv041Engebretsen KV, Lunde IG, Strand ME, Waehre A, Sjaastad I, Marstein HS, Skrbic B, Dahl CP, Askevold ET, Christensen G, Bjørnstad JL, Tønnessen T (2013)
Lumican is increased in experimental and clinical heart failure, and its production by cardiac fibroblasts is induced by mechanical and proinflammatory stimuli
FEBS J, 280 (10), 2382-98
PubMed
23480731 DOI
10.1111/febs.12235