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Showing 1–10 of 12 results

Doctoral Thesis

PhD defence: Camilla Udjus

Cand.med. Camilla Udjus will be defending the thesis “Hypoxia-mediated inflammation in pulmonary hypertension: From mice to mountaineers” for the degree of PhD (Philosophiae Doctor).

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New publications

Towards new treatments for cardiac fibrosis: ADAMTS4 inhibition in heart failure

Maria Vistnes, Pugazendhi Murugan Erusappan, Athiramol Sasi, Einar Sjaastad Nordén, Kaja Bergo, Andreas Romaine, Ida Gjervold Lunde, Lili Zhang, Maria Belland Olsen, Jonas Øgaard, Cathrine Rein Carlson, Christian Hjorth Wang, Jon Riise, Christen Peder Dahl, Arnt Eltvedt Fiane, Ida Marie Hauge-Iversen, Emil Espe, Arne Olav Melleby, Theis Tønnessen, Jan Magnus Aronsen, Ivar Sjaastad, Geir Christensen

Inhibition of the extracellular enzyme ADAMTS4 prevents cardiac fibrosis and dysfunction

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Seminars and conferences

IEMR – Project meeting,
Donald Gullberg

16. june 2023

“An update in fibroblast biology”

 

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New publications

A novel understanding of the matrix protein lumican in hypertrophic cardiomyopathy (HCM)

Rixon C, Andreassen K, Shen X, Erusappan PM, Almaas VM, Palmero S, Dahl CP, Ueland T, Sjaastad I, Louch WE, Stokke MK, Tønnessen T, Christensen G, Lunde IG

Lumican accumulates with fibrillar collagen in fibrosis in hypertrophic cardiomyopathy

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New publications

Cardiomyocyte-specific overexpression of syndecan-4 in mice results in activation of calcineurin-NFAT signalling and exacerbated cardiac hypertrophy

Lunde IG, Aronsen JM, Melleby AO, Strand ME, Skogestad J, Bendiksen BAAhmed MS, Sjaastad I, Attramadal H, Carlson CR, Christensen G.

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In focus

The challenge of stiff hearts

The Christensen group at IEMR aims to increase our understanding of the processes that lead to cardiac stiffening and to develop new treatments for this major challenge.

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New publications

Dual-receptor targeting of mechanoreceptors to reduce cardiac remodeling

Andreas Romaine, Arne Olav Melleby, Jahedul Alam, Viola Hélène Lobert, Ning Lu, Francesca E. Lockwood, Almira Hasic, Ida G. Lunde, Ivar Sjaastad, Harald Stenmark, Kate M. Herum, Donald Gullberg and Geir Christensen

Integrin α11β1 and syndecan-4 dual receptor ablation attenuate cardiac hypertrophy in the pressure overloaded heart

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New publications

Cardiac masses and function after expedition to extreme altitude

Camilla Udjus, Ivar Sjaastad, Ulla Hjørnholm, Torbjørn K. Tunestveit, Pavel Hoffmann, Alexis Hinojosa, Emil K.S. Espe, Geir Christensen, Ole Henning Skjønsberg, Karl-Otto Larsen and Morten Rostrup

Extreme altitude induces divergent mass reduction of right and left ventricle in mountain climbers

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People

People at IEMR: Athiramol Sasi

Researcher Athiramol Sasi borrowed tricks from a documentarist and a president when she prepared for an important presentation. At IEMR, we learn from the best!

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Seminars and conferences

IEMR – Project meeting
professor Carl-Henrik Heldin

  1. November 2021

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