News archive | Institute for Experimental Medical Research (IEMR)

General

Pop-sci from IEMR: Enough Covid. We need to talk about heart failure.

For two years, the world has focused on one disease. It’s the time to remind ourselves of other diseases that will stay with us even after the pandemic. Professor at IEMR, Mathis Korseberg Stokke, suggests we start with heart failure.

Doctoral Thesis

PhD Defence: Karoline Bjarnesdatter Rypdal

Msc Karoline Bjarnesdatter Rypdal at Institute of Clinical Medicine has defended the thesis “Connective tissue disorders and cardiac fibrosis: Genetic substrate and roles of ADAMTSL2 and ADAMTSL3 in the failing heart” for the degree of PhD (Philosophiae Doctor).

March 18, 2022

General

FACS – new method and equipment

The heart contains more than 20 different cell types and sub-populations. Separating different cell types from each other allows more precise analysis of the cells.

General

A steady-handed robot for faster and more precise genotyping

A new method for genotyping is now being implemented at the Laboratory and Technical sections at IEMR. It is faster, more reliable and reduces cost.

New publications

Cardiac masses and function after expedition to extreme altitude

Camilla Udjus, Ivar Sjaastad, Ulla Hjørnholm, Torbjørn K. Tunestveit, Pavel Hoffmann, Alexis Hinojosa, Emil K.S. Espe, Geir Christensen, Ole Henning Skjønsberg, Karl-Otto Larsen and Morten Rostrup

Extreme altitude induces divergent mass reduction of right and left ventricle in mountain climbers

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New publications

New imaging technology can shoot close-ups of myocardial function

Markus Borge Harbo, Mathis Korseberg Stokke, Ivar Sjaastad, Emil Knut Stenersen Espe

One step closer to myocardial physiology: From PV loop analysis to state-of-the-art myocardial imaging

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New publications

Riding the Tube: Cardiac Transverse Tubules in Physiology and Heart Failure

Katharine M. Dibb, William E. Louch, Andrew W. Trafford

Cardiac Transverse Tubules in Physiology and Heart Failure

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People

People at IEMR: Mani Sadredini

Mani Sadredini started at IEMR as a research curriculum student, and is now in the final stretch of his PhD.

General

UiO blog: The heart’s rythm is the rythm of life – always changing

The heart is like a jazz bands attentive rythm section: Always responding to impulses from the rest of the body. But how?

New publications

A potential anti-fibrotic role for ADAMTSL2 in heart failure

Karoline B. Rypdal, Pugazendhi M. Erusappan, A. Olav Melleby, Deborah E. Seifert, Sheryl Palmero, Mari E. Strand, Theis Tønnessen, Christen P. Dahl, Vibeke Almaas, Dirk Hubmacher, Suneel S. Apte, Geir Christensen & Ida G. Lunde

The extracellular matrix glycoprotein ADAMTSL2 is increased in heart failure and inhibits TGFβ signalling in cardiac fibroblasts

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