A potential anti-fibrotic role for ADAMTSL2 in heart failure
Karoline B. Rypdal, Pugazendhi M. Erusappan, A. Olav Melleby, Deborah E. Seifert, Sheryl Palmero, Mari E. Strand, Theis Tønnessen, Christen P. Dahl, Vibeke Almaas, Dirk Hubmacher, Suneel S. Apte, Geir Christensen & Ida G. Lunde
The extracellular matrix glycoprotein ADAMTSL2 is increased in heart failure and inhibits TGFβ signalling in cardiac fibroblasts
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A new concept of CaMKII regulation and a crucial role of AKAP18δ in regulation of the heartbeat
Cathrine R. Carlson, Jan Magnus Aronsen, Anna Bergan-Dahl, Marie Christine Moutty, Marianne Lunde, Per Kristian Lunde, Hilde Jarstadmarken, Pimthanya Wanichawan, Laetitia Pereira, Terje RS Kolstad, Bjørn Dalhus, Hariharan Subramanian, Susanne Hille, Geir Christensen, Oliver J. Müller, Viacheslav Nikolaev, Donald M. Bers, Ivar Sjaastad, Xin Shen, William E. Louch, Enno Klussmann and Ole M. Sejersted
AKAP18δ anchors and regulates CaMKII activity at phospholamban-SERCA2 and RYR
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IEMR anniversary: 70 years of translational research
In 2021, the Institute for Experimental Medical Research celebrates its 70 year anniversary. Since its foundation in 1951, the institute has developed into one of Norways largest and most successful research environments. Professor Emeritus and former Head of IEMR, Ole M. Sejersted reflects on what brought the institute to its current position.
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People at IEMR: Athiramol Sasi
Researcher Athiramol Sasi borrowed tricks from a documentarist and a president when she prepared for an important presentation. At IEMR, we learn from the best!
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New opportunities at IEMR: Full circuit at the Core facility for large animal research
The IEMR way is excellent cardiac research from bench to bedside. “And back again!” adds Professor Mathis Korseberg Stokke, fired up by recent events at the Core facility for large animal research.
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People at IEMR: Chloe Louise Rixon
British Chloe Louise Rixon found that IEMR ticked all her boxes when looking for a PhD-project. She added a winter coat and warmed up to the idea of being a researcher in Norway.
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People at IEMR: Michael Frisk
Michael Frisk‘s main research focus has been cellular structures in heart muscle cells called T-tubuli, which are important for calcium handling. Recently, he has received a prestigious career stipend from the Norwegian Research Council to investigate mechanisms for heart disease in salmon.
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