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New imaging technology can shoot close-ups of myocardial function

Markus Borge Harbo, Mathis Korseberg Stokke, Ivar Sjaastad, Emil Knut Stenersen Espe

One step closer to myocardial physiology: From PV loop analysis to state-of-the-art myocardial imaging

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State-of-the-art cardiac imaging makes it possible to assess myocardial function at a level of detail not seen before.

Measurements of left ventricular (LV) work, efficiency, stiffness and contractility from pressure-volume (PV) loops is the gold standard for assessing left ventricular (LV) function. However, use is limited because of the need for invasive left ventricular catheterization. Through advances in cardiac imaging it has become possible to measure these functional aspects non-invasively. In addition, state-of-the-art imaging technology can directly assess regional differences in myocardial function. This makes it possible to go beyond the measurements of global chamber function, as is done with PV loops, and assess myocardial function at a level of detail not seen before.

Acta Physiol (Oxf), 234 (2), e13759
PubMed 34978759 DOI 10.1111/apha.13759

Markus Borge Harbo

Medical Research Curriculum Student

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Emil Espe

Postdoctoral fellow

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Institute for Experimental Medical Research

Oslo University Hospital, Ullevål

PB 4956 Nydalen

NO-0424 Oslo

Norway

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