Kaja K. Bergo; Anne C. Larstorp; Pavel Hoffmann; Ulla Hjørnholm; Alessandro Cataliotti; Aud Høieggen; Morten Rostrup and Fadl Elmula M. Fadl Elmula
Renal sympathetic denervation (RDN) is again gaining interest as recent well-designed trials have demonstrated reduced ambulatory blood pressure (BP) after RDN. However, the hemodynamic mechanisms have not been elucidated. We aimed for the first time to investigate the effect of RDN on the “Hallmark of Hypertension” namely increased systemic vascular resistance index (SVRI).
Our data suggest that in patients with true treatment-resistant hypertension, renal sympathetic denervation lowers BP by reducing systemic vascular resistance of similar size as in the control group with careful individual selection of antihypertensive drugs and dose titration.
Read the article in Blood Pressure