Image: Profile picture of Mani Nikoo Sadredini

Mani Sadredini

Doctoral Research Fellow

Stokke group

Email: mani.sadredini@medisin.uio.no
Phone: 230 16831

Academic interests: Cardiomyocyte calcium handling and arrhythmias with special focus on cardiac ryanodine receptors.

Research area

  • Arrhythmias
  • Cardiomyocyte signaling
  • Electrophysiology
  • Excercise physiology
  • Excitation contraction coupling
  • Genetic cardiology
  • Heart failure
  • Ischemic heart disease

Latest publications

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Haugsten Hansen M, Sadredini M, Hasic A, Anderson ME, Sjaastad I, Korseberg Stokke M (2022)
CaMKII and reactive oxygen species contribute to early reperfusion arrhythmias, but oxidation of CaMKIIδ at methionines 281/282 is not a determining factor
J Mol Cell Cardiol, 175, 49-61
PubMed 36528076 DOI 10.1016/j.yjmcc.2022.12.002
Sadredini M, Manotheepan R, Lehnart SE, Anderson ME, Sjaastad I, Stokke MK (2021)
The oxidation-resistant CaMKII-MM281/282VV mutation does not prevent arrhythmias in CPVT1
Physiol Rep, 9 (18), e15030
PubMed 34558218 DOI 10.14814/phy2.15030
Sadredini M, Haugsten Hansen M, Frisk M, Louch WE, Lehnart SE, Sjaastad I, Stokke MK (2021)
CaMKII inhibition has dual effects on spontaneous Ca2+ release and Ca2+ alternans in ventricular cardiomyocytes from mice with a gain-of-function RyR2 mutation
Am J Physiol Heart Circ Physiol, 321 (2), H446-H460
PubMed 34270372 DOI 10.1152/ajpheart.00011.2021
Danielsen TK, Sadredini M, Manotheepan R, Aronsen JM, Frisk M, Hansen MH, Andressen KW, Hougen K, Levy FO, Louch WE, Sejersted OM, Sjaastad I, Stokke MK (2021)
Exercise Training Stabilizes RyR2-Dependent Ca2+ Release in Post-infarction Heart Failure
Front Cardiovasc Med, 7, 623922
PubMed 33569394 DOI 10.3389/fcvm.2020.623922
Ottesen AH, Carlson CR, Eken OS, Sadredini M, Myhre PL, Shen X, Dalhus B, Laver DR, Lunde PK, Kurola J, Lunde M, Hoff JE, Godang K, Sjaastad I, Pettilä V, Stridsberg M, Lehnart SE, Edwards AG, Lunde IG, Omland T, Stokke MK, Christensen G, Røsjø H, Louch WE (2019)
Secretoneurin Is an Endogenous Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor That Attenuates Ca2+-Dependent Arrhythmia
Circ Arrhythm Electrophysiol, 12 (4), e007045
PubMed 30943765 DOI 10.1161/CIRCEP.118.007045
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