Image: Profile picture of Francesca Lockwood

Francesca Lockwood

Doctoral Research Fellow


PhD Student at University of Oslo / Oslo University Hospital.

Doctoral research interests:
The mechanisms involved in syndecan-4 mechanosensing and myofibroblast activation leading to cardiac fibrosis.

Ida Gjervold Lunde, IEMR
Geir Christensen, IEMR
Viola Lobert, OsloMet

Research area

  • Cell signaling
  • Diastolic dysfunction
  • Fibroblast signaling
  • Fibrosis
  • Imaging

Latest publications

Støle TP, Lunde M, Shen X, Martinsen M, Lunde PK, Li J, Lockwood F, Sjaastad I, Louch WE, Aronsen JM, Christensen G, Carlson CR (2022)
The female syndecan-4-/- heart has smaller cardiomyocytes, augmented insulin/pSer473-Akt/pSer9-GSK-3β signaling, and lowered SCOP, pThr308-Akt/Akt and GLUT4 levels
Front Cell Dev Biol, 10, 908126
PubMed 36092718 DOI 10.3389/fcell.2022.908126
Romaine A, Melleby AO, Alam J, Lobert VH, Lu N, Lockwood FE, Hasic A, Lunde IG, Sjaastad I, Stenmark H, Herum KM, Gullberg D, Christensen G (2022)
Integrin α11β1 and syndecan-4 dual receptor ablation attenuate cardiac hypertrophy in the pressure overloaded heart
Am J Physiol Heart Circ Physiol, 322 (6), H1057-H1071
PubMed 35522553 DOI 10.1152/ajpheart.00635.2021